Cohesin is a ring-shaped protein complex involved in the spatial organization of the genome and in mitotic chromosome structure. Vertebrate somatic cells have two versions of cohesin that contain either SA1 or SA2, but their functional specificity has …
A new class of cancer drug which targets a faulty gene might be effective in treating some aggressive pancreatic cancers, researchers from Cancer Research UK’s Cambridge Research Institute and the Wellcome Trust Sanger Institute reported in the journal…
A team of scientists led by Johns Hopkins researchers have found that more than four in 10 people considered at high risk for hereditary pancreatic cancer have small pancreatic lesions long before they have any symptoms of the deadly disease. Moreover,…
Researchers at Moffitt Cancer Center have carried out a study to validate the utility of new tumor classification systems for staging and predicting relapse-free survival for patients with neuroendocrine tumors (NETs) and who may be candidates for surg…
Oncologists who treat patients with pancreatic cancer may be one step closer to understanding why gemcitabine, the only currently available treatment, works in some cases but not in others, according to a paper in Cancer Discovery, a journal of the Ame…
Scientists have connected two signature characteristics of pancreatic cancer, identifying a self-perpetuating “vicious cycle” of molecular activity and a new potential target for drugs to treat one of the most lethal forms of cancer. The research, repo…
Scientists at The University of Texas MD Anderson Cancer Center have identified a self-perpetuating “loop” of molecular activity that fuels pancreatic cancer by linking two signature characteristics of the disease – Kras, a gene that serves as a molecu…
Ben Stanger, MD, PhD, assistant professor of Medicine in the Division of Gastroenterology at the Perelman School of Medicine, University of Pennsylvania, and Andrew Rhim, MD, a Gastroenterology Fellow in the Stanger lab, discovered that pancreatic canc…
According to a study published in the British Journal of Cancer, individuals who consume too much processed or red meat may have an increased risk of developing pancreatic cancer. Researchers discovered that compared to individuals who ate no meat, …
ONCOLOGY: KRAS provides maintenance for pancreatic cancer The outlook for individuals diagnosed with the most common form of pancreatic cancer, pancreatic ductal adenocarcinoma (PDA), is very poor; the average time of survival after diagnosis is less …
