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Entries for the ‘Genetics’ Category

Personal Genetic Test Results Have Not Driven Overuse Of Expensive Medical Care

People have more and more chances to participate in genetic testing that can indicate their range of risk for developing a disease. Receiving these results does not appreciably drive up – or diminish – test recipients’ demand for potentially costly fol…

Rare DNA Variations May Be Responsible For Differences In Susceptibily To Heart, Lung And Other Disorders

One-letter switches in the DNA code occur much more frequently in human genomes than anticipated, but are often only found in one or a few individuals. The abundance of rare variations across the human genome is consistent with the population explosion…

Working To Understand A Rare Genetic Disease, Scientists Uncover The Most Common Fault In DNA Replication

Scientists from the Medical Research Council (MRC) Institute of Genetics and Molecular Medicine (IGMM) at the University of Edinburgh have discovered an enzyme that corrects the most common mistake in mammalian DNA. The mistake is the inclusion of indi…

Gene Expression By Ultraviolet

Imagine being able to control genetic expression by flipping a light switch. Researchers at North Carolina State University are using light-activated molecules to turn gene expression on and off. Their method enables greater precision when studying gen…

Focusing on PARP-1 Reveals Potential New Drug Targets

A new study published in Science is shedding light on the molecular details of PARP-1, a DNA damage-detecting enzyme that when inhibited has been shown to be effective in fighting cancer and other diseases. The investigation led by John M. Pascal, Ph.D…

MiR-TRAP Allows Scientists To Better Understand The Roles MicroRNAs Play In Human Development And Disease

Human cells are thought to produce thousands of different microRNAs (miRNAs) – small pieces of genetic material that help determine which genes are turned on or off at a given time. miRNAs are an important part of normal cellular function, but they can…

Preventing The Passing Of Mitochondrial Mutations From Mother To Child

Research conducted at the Oregon National Primate Research Center at Oregon Health & Science University helps answer some long-standing questions about how certain disease-causing gene mutations are inherited. The research specifically focused on gene …

International Project To Write A Landmark Sequel To ‘The Book Of Life’

Scientists are announcing the roadmap, policies and procedures for an ambitious international project that aims to compile a landmark sequel to “The Book of Life.” The follow-up to the Human Genome Project, which decoded all of the genes that make up h…

A Small Cut With A Big Impact

Diseases and injuries trigger warning signals in our cells. As a result, genes are expressed and proteins produced, modified or degraded to adapt to the external danger and to protect the organism. In order to be able to produce a particular protein, t…

Red Wine Anti Aging Properties Confirmed

Good news for wine drinkers the world over. New research is showing the properties of a chemical present in red wine, known as resveratrol, does indeed have anti-aging properties. It was always postulated that resveratrol had benefits, but the questio…